American Cruise Lines specialises in a unique style of small ship cruising along the inland waterways and rivers of the United States.  Itineraries include the Pacific Northwest, Maine, New England Islands, Hudson River, Chesapeake Bay, the Historic South & Golden Isles, Florida, Alaska, and the Mississippi River.

The 6 modern ships, each carrying no more than 150 passengers, have comfortable lounges and large observation decks and are designed to navigate where larger ships could never go.